Treatments › Autologous serum drops

Autologous serum drops for dry eye

Eye drops made from your own blood serum, used for more severe or persistent dry eye.

Autologous serum drops are eye drops made from a sample of your own blood, processed to separate out the serum, which is then diluted and bottled as eye drops. Serum contains growth factors and proteins similar to natural tears, which is the theory behind its use.

Getting started involves a blood draw at a pathology provider, followed by compounding into individual drop bottles, usually through an ophthalmology-linked service. Drops are then used several times a day and stored frozen or refrigerated between uses.

This treatment is generally reserved for more severe or persistent dry eye that hasn't responded well to standard drops or in-clinic procedures. It's usually arranged through or alongside an ophthalmologist, and a clinician will discuss suitability, storage and cost before proceeding.

Best for

Severe or persistent dry eye not responding to standard treatments

Typical cost

Often $200–$400+ for an initial batch of drops, with ongoing costs for repeat blood draws. Pricing varies by compounding pharmacy.

Costs are indicative: confirm with the clinic.

Frequently asked questions

Do I need a referral for serum drops?

Many clinics arrange this in conjunction with an ophthalmologist, so a referral is often part of the process. Ask your clinic directly.

How are the drops stored?

Serum drops are typically kept frozen in small batches and thawed a bottle at a time in the fridge, following your clinic’s instructions.

Is the blood draw painful?

It's a standard blood draw similar to a routine blood test, generally done at a pathology collection centre.

Common questions

Still working out whether this is the right step? These plain-English guides help.

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This page is general information, not medical advice. See a qualified clinician to find out what is right for you.